Welcome
Welcome to the BHF Centre of Research Excellence Bioinformatics Team at the Queen's Medical Research Institute at the University of Edinburgh, Scotland, UK. We are based in the University / BHF Centre for Cardiovascular Science and funded by the British Heart Foundation (BHF Centre of Research Excellence).
Our team has co-authored 17 peer reviewed papers including recent high impact work in the European Heart Journal, Diabetes, and the Journal of the American Society of Nephrology (JASN).
Bioinformatics publications
- Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR Review 1.
- Optimal Elevation of β-Cell 11β-Hydroxysteroid Dehydrogenase Type 1 Is a Compensatory Mechanism that Prevents High Fat Diet-Induced β-Cell Failure.
- Drosophila poly suggests a novel role for the Elongator complex in insulin receptor–target of rapamycin signalling
- Hyperglycemia and Renin-Dependent Hypertension Synergize to Model Diabetic Nephropathy.
- A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies novel candidate obesity genes.
- Novel Fat Depot-Specific Mechanisms Underlie Resistance to Visceral Obesity and Inflammation in 11{beta}-Hydroxysteroid Dehydrogenase Type 1-Deficient Mice.
- A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE Genetics Study.
- Transcriptional and physiological responses to chronic ACTH treatment by the mouse kidney.
